EP-1161 Clinical response and toxicity of VMAT lowdose RT with intravenous steroids for Graves’ Orbitopathy
نویسندگان
چکیده
منابع مشابه
Clinical and imaging evaluation of the response to intravenous steroids in patients with Graves’ orbitopathy and analysis on who requires additional therapy
OBJECTIVE The aim of this study was to evaluate the safety and efficacy of an individualized steroid regimen in patients with moderate-to-severe Graves' orbitopathy (GO) by monitoring clinical and imaging parameters. METHODS In total, 47 patients with active, moderate-to-severe GO were enrolled in this study. All the patients received the proposed treatment regimen by European Group on GO of ...
متن کاملClinical assessment of patients with Graves' orbitopathy: the European Group on Graves' Orbitopathy recommendations to generalists, specialists and clinical researchers.
Clinical assessment of patients with Graves’ orbitopathy: the European Group on Graves’ Orbitopathy recommendations to generalists, specialists and clinical researchers The European Group on Graves’ Orbitopathy (EUGOGO): W M Wiersinga, P Perros, G J Kahaly, M P Mourits, L Baldeschi, K Boboridis, A Boschi, A J Dickinson, P Kendall-Taylor, G E Krassas, C M Lane, J H Lazarus, C Marcocci, M Marino,...
متن کاملGraves' Orbitopathy
1Division of Endocrinology and Metabolism, Department of Medicine, Kurume University School of Medicine, Kurume, Fukuoka 830-0011, Japan 2Department of Medicine, Nepean Clinical School, Nepean Hospital, The University of Sydney, Penrith, NSW 2751, Australia 3Molecular Thyroid Research Laboratory, Department of Medicine I, Johannes Gutenberg University (JGU) Medical Center, 55101 Mainz, Germany ...
متن کاملLiver Dysfunction Associated with Intravenous Methylprednisolone Pulse Therapy in Patients with Graves' Orbitopathy
Intravenous methylprednisolone (IVMP) pulse therapy is the first-line treatment for the active phase of moderate to severe Graves' orbitopathy (GO). However, acute and severe liver damage has been reported during and after IVMP therapy. In this retrospective study, we investigated risk factors for liver dysfunction during and after IVMP therapy based on 175 Japanese patients with moderate to se...
متن کاملMedical Treatment of Graves’ Orbitopathy
▼ The medical treatment of Graves’ orbitopathy (GO) is usually reserved to moderate to severe disease. Steroids have been widely employed and possess anti-inflammatory activity, but about 20–30 % of patients are not responsive and about 20 % present with disease recurrence. Immunosuppressive therapy alternative to corticosteroids may target the different antigens involved in pathogenic mechanis...
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ژورنال
عنوان ژورنال: Radiotherapy and Oncology
سال: 2019
ISSN: 0167-8140
DOI: 10.1016/s0167-8140(19)31581-6